Dahurian rose fruit

[ ] from the" Heilongjiang" of traditional Chinese medicine.
[ ] Pinyin name C M e I Gu I
English name [ ] Dahurian Rose Fruit, Fruit of Dahurian Rose
[ alias ] berry fruit, thorn wood fruit
[ source ] medicine source: for the Rosaceae plant Rosa davurica, light Ye Shan dahurian rose fruit.
Latin animal mineral name: Rosa davurica Pall.
Harvest and storage: fruit in mature off immediately, dried, dried or fresh fruit calyx removed, cut in half, remove the stones, and then drying.
[ ] the original morphology of 1 Rosa davurica erect shrubs, high 1-2m. Branches glabrous branchlets and petioles, base the Ministry has a pair of yellow prickles, thorns curved, base in. Pinnately compound leaves, leaf 7-9, even the petiole length 4-10cm; petiole and rachis pubescent, glandular hairs and sparse prickles; stipules adnate to petiole large, margin glandular serrate, following pubescent; leaflets - rounded or broadly lanceolate, long 1.5-3cm, 0.8-1.5cm wide, apex acute or obtuse, base broadly cuneate, margin nearly above middle have sharply serrate, glabrous above, ash green, glaucous, puberulent or glandular dots. Flowers solitary or several fascicled; petals pink about 4cm in diameter; leaf stalk with glandular hairs; styles free, slightly protruding stigmas torus export department. Fruit globose or ovoid, diameter 1-1.5cm, red. Sepals night latch, upright. Flowering 6-7. Fr. 8-9.
2 Ye Shan rose this mutation and Rosa davurica distinction: leaflets up to 4cm, the granular glands, usually glabrous, pubescent only along veins.
[ ] habitat distribution ecological environment: born in 1 in 430-2500m elevation slopes Yang or forest edges, hilly grassland.
Born in 2 in hillside Yang department.
Resource distribution: 1 located in the northeast, North China and other places.
2 distribution in the Northeast region.
[ character ] dry fruit spherical, wall hard brittle, orange red, diameter 1.2cm, seeds are furry, a total of about 24 grains. Sweet and sour flavor.
[ ] the chemical composition of Rosa davurica fruit contains organic acids, sugars, pectin, vitamin C, carotenoid, phenolic compounds leucoanthocyanidin (leucoanthocyanindin ), pigments ( anthocyanindin ) ( catechin ), catechin, trace elements ( calcium, magnesium fluoride, etc.), protein, silver Linden glycoside ( tiliroside ), the Ephedra tanning booths ( casuarictin ), 1, 2, 3, 6 - four - O - galloyl - beta - D - glucose ( 1, 2, 3, 6tetraO-galloyl - P - D-glucose), 1, 2, 3, 6, five O galloyl - beta - D - glucose ( 1, 2, 3, 4, 6-Penta-O-galloyl - P - D-glucose), agrimonine ( agrimoniin ), ( laevigatin ) of tannins in Fructus Rosae Laevigatae added D, F, dahurian rose fruit hormone ( davuriciin ) M / 1, D / 1, D / 2, T / 1, and oleanolic acid ( oleanolic acid ).
Pharmacological action [ ]
L. Anti-aging effects in in vitro trials, dahurian rose fruit powder can improve in cultured human lymphocytes and sheep erythrocyte superoxide dismutase ( SOD ) activity, particularly in the drug then cultured 12h results significantly. The integral test, in the culture medium added with 1% rose powder; the maximum and average lifespan of Drosophila significantly prolonged, rat serum lipid peroxide ( LPO ) content decreased, SOD activity in red blood cells. 2% rose fruit extract concentrated juice ( each LML is equivalent to 0.06g raw ) orally can improve mouse liver SOD activity, inhibition of mouse liver LPO and cardiomyocyte lipofuscin formation, and can significantly reduce the mouse tail tendon of hydroxyproline content. Dahurian rose fruit extract capsule 30d1 treatment, observe each other 1-3 courses, for the elderly subjective sensory changes, sleep, appetite, energy, physical strength is improved obviously, and can improve intelligence, especially to enhance the thinking and memory abilities and extrapyramidal features significantly, while on cardiopulmonary function also have different degrees of improvement. And the 70% to take the drug in biological age was significantly delayed in older people. On 60 years ago at the beginning of the older group effect is most obvious, up to a maximum of 11 years.
2 the role of the immune system of dahurian rose fruit extract 0.1g / only gavage continuous 7d, of textile noise reduce hemolysin content, lymphocyte, macrophage phagocytic rate and index is obviously improved. Experiments show that, dahurian rose fruit on noise induced immunosuppression has good centralizing effect. Dahurian rose fruit extract to match the 8% suspensions orally, can make the tumor-bearing mice T lymphocyte subsets, T ( T. ) Cell number increased, decreased T inhibition ( T / s ) cell number, increase T / H / Ts ratio, and the 60 / Co irradiated mice leukocytes decreased, and after radiation in the third returned to normal levels, description of Rosa davurica Pall. Could enhance the tumor-bearing mice cellular immune function. And the serum hemolysin level ( HC / 50 ) was significantly elevated, suggesting that it has enhanced the role of humoral immunity.
3 anticancer effect of ethanol extract of dahurian rose fruit, equivalent to the LG / ml dried fruit juice, in vitro simulated gastric conditions, can block the two methyl nitrosamines ( DMN ) synthesis, the blocking rate and rose juice volume has positive correlation ( r = 0.879 ). At 37 degrees C, the equivalent of 1.4g dahurian rose fruit juice (containing the 3mg vitamin C ) on the DMN synthesis blocking rate is 82.72%, and 3mg vitamin C blocking rate is only 20.66%. In vitro under the same conditions, rats, dahurian rose fruit juice blocking rate was 98.49%, Vc was 9.04%, suggestive of Rosa davurica Pall. Could significantly blocking the synthesis of DMN, and juice in addition to vitamin C, may contain blocking effects more unknown components. In addition, by enhancing the free radical scavenging ability of immune ability, and can resist the urethane induced mouse lung adenomas, and the induced cancer of mice peripheral blood SOD activity, glutathione peroxidase ( GSH-Px ) activity, serum soluble elevated blood levels. The Lpo content decreased. Dahurian rose fruit water concentrated extract 1.44g / kg free drinking, successive 3 weeks, there are 60 / Co radiated rat erythrocytes in SOD content and GSH-PX activity in whole blood, prove its L against radiation injury in mice. Tips of dahurian rose fruit can be used as a tumor chemotherapy and radiotherapy as adjuvant treatment agent.
4 Effect on cardiovascular system of dahurian rose fruit extract 1ml village when in 2G crude drug, alcohol extract 1ml corresponds to the LG crude drug injection, having a relaxation of rabbit aortic strips in rats, reduce blood pressure and cerebral vascular resistance, increased coronary blood flow, reducing the cat coronary resistance role. Inhibition of free atrial contraction, slow heart rate, against rabbit posterior pituitary hormone induced myocardial ischemia during S-T period, against mouse normobaric hypoxia and isoproterenol induced hypoxia effects, and inhibition of rabbit platelet gathering and thrombosis in rats, its effective component and contains flavone compounds related to.
5 liver function can reduce the experimental carbon tetrachloride, ethanol, nitrite rubber and other damage to the liver, changes in human serum alanine aminotransferase ( ALT ) and turbidity abnormalities, reduce and eliminate the degeneration and necrosis of liver cells, reduce inflammation and fibrosis, the liver protective effect of oleanolic acid on its rich. To give sodium nitrite and aminopyrine in serum of rats with ALT and sorbitol dehydrogenase ( SDH ) activity than normal group increased 1 times, and cause liver cell degeneration and necrosis, under the same conditions, the same to rose juice of ALT rats and SDH vitality to maintain normal levels, liver cells also did not suffer injury.
6 anti fatigue, anti hypoxia effect of dahurian rose fruit dry powder by ethanol refluxing extraction, ethanol recovery followed by ethyl acetate after the residue into l% suspension, mouse peritoneal injection of 0.5ml, 2h, hypoxia tolerance in mice experimental survival time was significantly higher than that in the control group, and in mouse loading swimming test, swimming time was significantly higher than that of the control group.
7 other of anti-inflammatory on formaldehyde-induced arthritis in rats effectively. The rose fruit gavage can obviously promote the metabolism of nucleic acids and proteins in mouse bone marrow cells. The rose fruit extraction and separation of pure products of silver Linden glycoside, on the culture conditions of human embryonic lung fibroblasts ( 2BS-C ) in DBA damage repair, 8h began to have effect on DNA repair, 24h growth rate increased significantly. Dahurian rose fruit juice in rats with gastric can significantly stopped two methyl nitrosamines ( DMN ) synthesis, Yin its fault rate is 98.49%, dahurian rose fruit in vitro tests have the same shade off DMN synthesis.
8 toxicity of rose water and alcohol extracts the mouse intravenous injection, its LD / 50 respectively 4.5 ( 4-5 ) g / kg and 5 ( 4.3-5.8 ) g / kg, dahurian rose fruit flavones mouse intravenous injection of LD / 50 is a 956 ( 872-1048 ) mg / kg. Subacute toxicity test shows that, the heart, liver, kidney organ toxicity reaction.
[ ] toxicity toxicity: the mouse intravenous injection, dahurian rose fruit water extract of LD50 4.5g / kg, dahurian rose fruit alcohol extract of LD5.0 g / kg.
[ ] acid taste bitter; temperature;
[ ] to the liver; spleen; stomach; bladder
[ function ] Jianpi Xiaoshi; Huoxue Tiaojing; astringing lung. The main indigestion; anorexia; abdomen distending pain; diarrhea; menstruation; dysmenorrhea; atherosclerosis; tuberculosis cough
[ usage]: orally taken decoction, 6-10g.
[ ] the discussion
1" Heilongjiang": Traditional Chinese medicine to help digestion. Treating infantile indigestion.
2" Handbook of common Chinese herbal medicines" Spleen Qi, nourishing blood and regulating menstruation. For indigestion, and diarrhea, stomach pain, abnormal menstruation.
Excerpts from" Chinese Materia Medica" [ ]


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