Northeast of Tripterygium wilfordii

[ ] Pinyin name Dō n Bě I Lé I G Té nō n
[ source ]
Medicine medium source: Celastraceae plant northeast of Tripterygium wilfordii root or the whole plant.
Latin botanical mineral name: Tripterygium Regelii Spragus animal et Takeda
Harvest and storage: the year may adopt. Root slicing or peeling dry, dry Tengqie section.
[ ] the original morphology of northeast of Tripterygium wilfordii vine shrub, plant height of about 2m. Branches brown, branchlets reddish brown, often Chengliu prismatic, glabrous, lenticels small verrucous. Ye Husheng1-4cm; petiole long; leaf blade oblong to obovate,5-20m long,3-12cm wide, apex caudate or acuminate, margin with irregular obtusely serrate, base rounded. Terminal thyrses, long 10-30cm, flowers polygamous, white and green, a diameter of about5mm; calyx 5; petals 5; stamens 5, inserted on shallow cup-shaped disk edge depends on the exterior; hermaphrodite flower ovary has 3 edge. Capsule with 3membranous wings, long 2-1.5cm, edge microwave shape. Seed long column shaped, dark red. Florescence 7-8 month, month of fruit period 8-9.
[ ] habitat distribution
Ecological environment: in montane forest edges, roadsides, coniferous or deciduous conifer mixed forest margins or in the forest.
Resource distribution: distribution in Northeast china.
[ character ]
Character identification of stem and branch is in a cylindrical shape, diameter 2-6mm. Old branches grayish brown or brown, internodes 4-9cm; surface processes of the dot shape or a longitudinal long punctate lenticels,5-6longitudinal ridge, leaf scars raised, alternate, semiorbicular or reniform, leaf axils often Youya, ovate-triangular, or branched; branches of current year brown or reddish brown color, sometimes visible ash green leaves, often broken, to complete the flattened oblong, ovate or obovate,6-15CM long,3-10cm wide, base broadly cuneate or rounded, apex acute or irregular in shape; petiolar long 1-2cm. Stem quality hard, difficult to break, section of skin is thin, pale brown, wood clement, yellow-white; pith large, pale brown or nearly white. Gas micro, mild.
Microscopic identification of annual transverse section of stem epidermal cells:1 column, outside the stratum corneum, wall light brown or brown, often convex outer wall; non glandular hair short and straight. Lateral series of cortical cell wall is light brown or brown, often slightly thickened at the corner, is not very typical collenchyma; each corner has 1bundles of fibers, fiber cell wall thickness. Cork tissue occurs in the cortex, the cell wall is thin, pale brown or brown. Vascular tissue continuous ring. Phloem fiber bundle lateral visible, almost continuous ring, fiber cell wall thickness, non wood. Secondary xylem fiber number. Medullary wide; its foreign myelin tissue, cells are smaller, slightly thickened wall, often lignified, containing starch granule. The parenchyma cells with calcium oxalate crystal ( phloem more ), the diameter of 6-20μ M. Biennial transverse section of the stem: epidermal and lateral cortical tissue often radial breaking, breaking away from the inner side part of cork tissue formed 1thick cell wall layer. Xylem visible rings.
[ ] root chemical composition containing black vine alcohol ester ( regelinol ), black vine lactone (regelide), black vine ketone ester ( regelin ) A, black vine ketone ester C and D ( regelin C, D ), black vine glycol ester A and B ( regelinoliol A, B ), black man fixed alkali ( regelidine ), A and B triptolide ( wilforlide A, B ),3 β - hydroxy -11,13(18) - Olive diene (3 β -hydroxy-olean-11-13(18) diene ), straight wedge oxalic acid (orthosphenic acid ), O Ko five ( salaspermic acid ) dragon acid,3 β - hydroxy Olean -12- allyl -29- carboxylic acid (3-epikatonic acid ), Maytenus variable leaf acid ( maytenfolic acid ),3 β- acetyl - oleanolic acid (3 β -acetyl-oleanolic, acid ) celastrol ( celastrol). In addition, also from the root was isolated in 6 of two diterpene quinone ( diterpenequinones ). Bark contains black vine alkali A, B, C ( tripterregeline A, B, C ). Stem xylem containing triptolide a - B ( wilforlide A, B ),β- sitosterol (β -sitosterol ), Dulcitol ( Dulcitol ). The entire plant polysaccharide containing ( polysaccharide ), glucose (D-glucose ) by D-, Arabia sugar ( arabinose ), galactose ( galactose ). The plant is also the Begonia hormone (hypolid) and Tripterygium wilfordii phenylpropanoid ( trinterolide ).
[ ] pharmacological effects in mice after subcutaneous injection of northeast Tripterygium wilfordii Decoction5-8 days, can make the thymic atrophy, interleukin 1( IL-1) induced proliferation of thymic cells, spleen cells by inhibition of concanavalin A ( ConA ) induced T cell proliferation in response to weaken, spleen cells to produce IL-2ability low, spleen T cells percent decrease. Show on cellular immune function inhibited. Mouse subcutaneous injection of northeast Tripterygium wilfordii Decoction on thymus-dependent ( TD ) induced by antigen quantitative hemolysis spectrophotometry ( QHS ) reaction and plaque forming cell ( PFC ) reaction was inhibited, but the thymus dependent antigen ( TI ) induced by QHS reaction, PFC reaction and Escherichia coli lipopolysaccharide ( LPS ) induced proliferative response of B cells do not significantly influence. Combined with the IL-2 production of splenocytes function inhibition, Northeast China on B cell function and no apparent direct inhibitory effect. The humoral immune inhibition is mediated through the inhibition of TH cell generation. For fetal cartilage extraction of type II collagen-induced rat experimental arthritis model, subcutaneous injection of northeast Tripterygium wilfordii decoction, can alleviate arthritis lesion degree, delayed the onset time, reduce the concentration of IgM in animal models, in vitro, inhibit ConA induced rat blood mononuclear cell proliferation, inhibition of mononuclear cells derived from IL-2activity, but on LPS induced rat blood mononuclear cell proliferative response showed no significant inhibition.
[ ] bitter taste; Xin; cool; toxic
[ ] to the liver; bile; spleen meridian
[ indications ] Qufeng desiccant; and water swelling; insecticidal toxin. The main rheumatoid arthritis edema; expansion; jaundice; mass in the abdomen; traumatic injury; Luo Li; sore throat; tinea capitis; pruritus; snake bites
[ usage]: orally taken decoction,1-6g. External application: suitable, grind end tune apply; or trace and apply; or Daozhi coated.
[ note ] oral administration should be carefully, external time should not exceed30 minutes. " Changbai Mountain plant medicine annals:" be careful".
Excerpts from" Chinese Materia Medica" [ ]
http://chinese-herbal-medicines-directory.blogspot.com/