Cephalotaxus sinensis leaves

[ ] C Pinyin name F I Zh Y reports keyword
[ source ]
Medicine source: three tips of Taxodiaceae Cephalotaxus sinensis leaves.
Latin animal mineral name: Cephalotaxus sinensis ( Rehd.et Wils. ) Li [C.drupacea Sieb.et Zucc.var.sinensis Rehd.et Wils.]
Harvest and storage: the year or summer and autumn harvest, dried.
[ ] the original morphology of shrubs or small trees, high up to 15m. Bark gray or gray-brown, split into flakes off. Leaves linear,2 rows, long 2-5cm, width of3mm, upper gradually narrow, apex acuminate or slightly convex tip, base subrounded, thick, dark green above, midrib is apparent, the following2 white stomatal bands, a green edge bandwidth 2-4times. The male cones6-7aggregated into capitula, diameter of about 6mm, total stem length of about3mm; the male cones ovoid, base the Ministry has1bracts, stamens4-11; female ball flower heads, usually 2-5ovule development becomes a seed. Seed 2-5, born in total stem top, oval, elliptical ovoid or subglobose, apex long 1.8-2.5cm, central cusp. 3-410-11flowering, seed maturity.
[ ] habitat distribution
Ecological environment: distribution of Yu Changjiang Valley South to Guangdong, Guangxi, West to Gansu, Shaanxi, Henan, Sichuan, Yunnan, Guizhou and other places.
Resource distribution: distribution of Yu Changjiang Valley South to Guangdong, Guangxi, West to Gansu, Shaanxi, Henan, Sichuan, Yunnan, Guizhou and other places.
[ ] leaves chemical composition containing three sharp cedar base ( cephalotaxine ), II - hydroxy three sharp cedar alkali ( II - hydroxycephaltaxine ), oxygen bridge three sharp cedar base ( drupacine ), to three sharp cedar methyl ketone alkali ( demethylcephalotaxinone ), C-3- table three Taiwan sharp cedar base ( C-3-epiwilsonine ), Taiwan three sharp cedar alkali ( wilsonine ). Bark contains Hainan Cephalotaxus lactone (hainanolide ), ISOHARRINGTONINE ( ISOHARRINGTONINE ), homoharringtonine ( homoharringtonine ). In addition, but also with harringtonine ( harringtonine ), DNA harringtonine ( deoxyharringtonine ).
[ ] from pharmacological effects of Cephalotaxus sinensis leaves the separation of the three sharp cedar alkali, homoharringtonine, ISOHARRINGTONINE pharmacological effects of total alkaloid agent Hainan Cephalotaxus sinensis against acute and chronic myeloid leukemia and malignant lymphoid disease have a certain effect.
[ ] taste bitter astringent; cold;
[ ] anticancer functions. Primary leukemia; malignant lymphoma
[ usage]
General extraction and its alkaloid made injection use, specific usage1treatment of leukemia with Chinese Cephalotaxus alkaloid daily 50-100mg intramuscularly, individual use to 200mg. In treatment of chronic myeloid leukemia in 11 cases, resulted in complete remission in 3 cases, partial remission of grade I, grade II in 2 cases, not relieved in 4 cases. Also found the goods on the CML blastic transformation also has good curative effect, with treatment of acute lymphoblastic leukemia in 10 cases, mostly with cyclophosphamide,6- mercaptopurine, hormone therapy, except 1 patients reached the improved to different degree, in which the complete remission in 6 cases. Observation of acute granulocytic white disease in 4 cases. Complete remission in 2 cases,5 cases of partial corrosion.
2treatment of polycythemia vera application of Cephalotaxus ester base Huang Zhi in 7 cases9, results in remission in 3 cases, effective in 4columns,1 cases were good times. Ease to good in 8 cases. To alleviate the need for an average of total drug65.5-133mg,97.8mg;32-42d,36d average. Effect of total drugs required for62.5-126mg, the average 92.5mg, time 28-50d, the mean 40d. Good effect on relapse cases, still valid. In conventional doses of side effects of light and short, it is a short remission period.
[ note ] the main toxicity was myelosuppression and gastrointestinal reaction, few patients can occur heart toxic reaction.
[ ] this product is attached side of plant morphology and fruit are similar and pistachio nuts, but ignored a Torreya rough, named Cephalotaxus sinensis. The seeds are edible and generation of Torreya, Torreya grandis called earth.
Excerpts from" Chinese Materia Medica" [ ]


http://chinese-herbal-medicines-directory.blogspot.com/