[ source ] Zhejiang" science and technology presentation of medical and health part"
[ ] Pinyin name Ch J n Xi n be be be n Q.
[ alias ] Bai Si edge front, maple eggplant incense.
[ source ] as the Compositae winged stems Xiangqing entire grass. Autumn.
[ ] the original morphology of perennial herbs, with a special aromatic, high 15~ 50cm. All strains were white woolly. Stems in clusters, a single unbranched. Leaves alternate, sessile, oblanceolate or linear-lanceolate,4 to9 cm long,0.6 to1 cm wide, apex obtuse and small cusp, base decurrent into wings, so that the stem angular. Inflorescence of health, most are arranged in a corymbose; unisexual or polygamous, all for the tubular flower, ca. 0.8cm, yellow. Involucral bracts bell,5, or 7 column, silver white. Achene with a small point. Fl. summer and fall.
[ ] habitat distribution was born in mountain and hilly areas. Distribution of Zhejiang.
[ ] the whole grass chemical composition containing volatile oil, glycosides, coumarin derivatives, reducing sugar, tannins and phenolic compounds.
Pharmacological action [ ]
Antitussive, expectorant, anti-asthma role.
Unilateral winged stems Xiangqing treatment of chronic bronchitis in more than 500 cases, efficiency is about 79%. After 1457cases of senile chronic bronchitis using various winged stems Xiangqing prescription and preparation, have a certain effect, clinical practice certificate and warped stems, Xiangqing is Bai Silun wind compound Chinese drug. Using sulfur dioxide as induced cough agent, winged stem Xiangqing Decoction liquid and compound preparation on mouse antitussive effect is not obvious, but its ethanol extract has stronger antitussive effect; winged stems Xiangqing Decoction expectorant effect than the compound is weak, its volatile oil and expectorant effects better ( mice phenol red determination ); winged stems Xiangqing Decoction total fluid of normal guinea pig tracheal smooth muscle is not constant, but on histamine induced tracheal smooth muscle contracture has obvious relief, which contain volatile oil has more apparent bronchial dilation effect; guinea-pig isolated trachea test proved, winged stem Xiangqing Decoction and total solution can only fight epsilon histamine phosphate effect (0.1%0.15~ 0.25ml ), increased histamine content, winged stem Xiangqing cannot antagonize its bronchial spasm. Can't fight the acetylcholine induced tracheal smooth muscle contraction.
The anti-inflammatory effect
Wing stem Xiangqing Decoction liquid in vitro of Staphylococcus and Staphylococcus aureus, Shigella sonnei, typhoid, paratyphoid bacillus, Escherichia coli have different degrees of inhibition ( test tube method, panel method). The essential part of antibacterial effect is poor, especially in the volatile oil of several no antibacterial effectiveness. Mouse peritoneal infection of Staphylococcus aureus, winged stem Xiangqing ethanol extract has obvious anti infection effect. Rabbit with its water decocted liquid, white blood cell count increased significantly.
The other effect
Wing stem Xiangqing ethanol extract can obviously effect on mouse locomotor activity, calm the phenomenon, but no obvious analgesia ( pain induced by acetic acid method, the hot plate method ). Its Decoction and total fluid and urethane and pentobarbital has obvious inhibiting central synergy; there is no anticonvulsant ( drugs); can weaken Nikethamide on respiratory function. Intravenous injection of winged stems Xiangqing Decoction and total fluid (1:1) can make in anesthetized rabbits blood pressure drops, also can reduce the rabbit respiratory volume. On isolated guinea pig intestines are inhibited, can obviously relieve histamine, acetylcholine. Barium chloride induced intestinal contracture. Wing stem Xiangqing Decoction and total fluid (1:2) mice, LD50of 80.52 g / kg; rabbit large gastric lavage, there may be loss of righting reflex, pain reflex is slow, limb paralysis, coma or respiratory pause, Nikethamide ( large) intravenous injection to save. The alcohol extract of low toxicity.
[ ] the antitussive expectorant, indications, asthma, inflammation. Treatment of cold, acute, chronic tracheitis, dysentery, enteritis.
[ ] the clinical application of treatment of chronic tracheitis: daily with winged stems Xiangqing dry goods 6money into single flavored syrup, or with a winged stem Holly 4money, Houttuynia6 money, Rhus chinensis1two compound decoction. Tablets and granules. All morning and evening 2minutes, course of treatment is 10 days, with two courses. The single, compound in different forms in different seasons in 2192 cases, treatment, medication for 20 days, the total efficiency of 75.6%, including the recent control on average 9.1%, effective in 19.5%. Driving observation, unilateral and compound effect there is no significant difference, but the single flavor syrup will winged stems Xiangqing dose increased to9.6 daily money, close control and significant efficiency can be improved significantly. Wing stem the antitussive, expectorant effect better Xiangqing, antiasthmatic effect is poor, the accident of course of diseases and therapeutic effect is not big, but the effect is slightly higher than that of pure type breather type, the efficacy of mild to severe. Part of the cases at 2 months and1 years after the review, efficiency drops ceaselessly, the recurrence rate gradually increased, mainly due to cold induced relapse. The main side effects for the dry throat, can disappear automatically, without the need for special treatment.
[ ] * dictionary" excerpt"
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