Menispermum dauricum

[ source ]" of" China Pharmaceutical Plant
[ ] Bi n F Pinyin name. G cabinet
[ alias ] bat cane (" Dan Liu test effect side" ), fishing (" gold gourd Chinese Medicine Pharmacology" ), a sweet, yellow, yellow root of Fangji Ge (" Chinese medicine plant records" ), (" pheasant beans Handbook of traditional Chinese medicines in Jilin" ), mountain climbing, mountain sweet potato vine plantings (" northeast annals of medicine plant" ), little Ge Xiang, willow tree (" son of Shandong Chinese traditional medicine" ), light WESTBANK grape vines, dog (" economic plants of Liaoning" ), Huang Tenggen, Huang Genteng, little ivy, Aristolochia koempeferi (" Zhejiang folk medicinal herbs commonly used" shit ), beans (" Chinese herbal medicines in Jilin" ), the horse Chuanling (" Chinese herbal medicines in Shaanxi" ), the gold hanging toad, even shoots ( Jiangxi" Handbook of herbs" ), Nimba ( by name ), GA Ma see agricultural stick ( in name ).
[ ] as a source of Menispermum dauricum DC cane. 8 ~ November cut cane, dried.
[ ] the original morphology of twining perennial herb, up to several meters, the whole plant nearly glabrous. Rhizome long, relatively thick, brown. Branchlets with longitudinal stripes. Leaves alternate, with the long handle, Shun shape, base cordate, apex acute, up to 6 ~ 12 ~ 15 cm, width of 6 ~ 12-17 cm, green above, paler below, after the leaves have small hair, smooth or on the back of yellow green furry. Flowers axillary, small shape, diameter of 3 ~ 4 mm, yellowish green, dioecious, flowers usually with calyx 6, 6 to 9 petals, stamens 20; female flowers usually with 3 carpels. Drupe kidney circle, diameter 1 cm, black. Florescence 5 to June. Fruit 7 to August.
[ ] on hillslopes habitat distribution, roadsides, in the bushes. The distribution of Liaoning, Jilin, Heilongjiang, Inner Mongolia, Hebei, Shandong, Shanxi, Henan, Jiangsu, Anhui, Zhejiang, Jiangxi, Fujian and other places. Made in Jiangsu.
[ character ] dried cane, cylindrical, diameter 2 to 10 mm. Surface yellowish brown to dark brown, with obvious longitudinal groove, festival with leaf scars, collateral marks or bud scars; qualitative hard, fractured surface fibrous skin, easy peeling, xylem vessel with hole shape, the white pulp. Sometimes basally slightly with a cylindrical root, diameter of 12 ~ 24 mm, surface grayish brown or brown, scabrous, longitudinally striate and rootlet mark; qualitative hard, section of powder, white, xylem holes are obvious. Gas with no, mild. To dry, brown, green branches, such as uniform coarse pinky is preferred.
[ ] the chemical composition of northeast of China and Japan Menispermum dauricum containing alkaloid Dauricine, tetrandrine, Dauricine, magnoflorine. Sinomenine, pointed leaves with tetrandrin, double sinomenine, light cepharanthine, to hydroxyl acumine.
Pharmacological action [ ]
Dauricine in anesthetized animals have hypotensive effect, pulse wave increases, breathing with transient exciting. The antihypertensive effect principle for central, at the same time also has direct effects on vascular dilatation ( 0.000001 ~ 0.00001 concentration can be expansion of rabbit isolated ear blood vessels). In addition, the ganglionic blockade ( 5 to 10 mg / kg can be blocked by the superior cervical ganglion of cat impulse conduction ) is undoubtedly caused blood pressure as a cause of. In clinic, the mild hypertensive patients effectively, make the glomerular filtration function better, but for serious patients with inactive. It inhibits the contraction of isolated rabbit intestine and decrease in intestinal tension, a spasmolytic effect. Can reduce blood cholesterol. Very little toxicity, treatment with larger width, cats intravenous minimum lethal dose of 35 mg / kg, after administration, animals ( especially mice and frogs ) manifestations of systemic excited, and then have a more long-term inhibition.
Dauricine as quaternary ammonium compounds, have good muscle relaxation ( rabbit head test ), the nature of its role and curare with. In dogs, cats, rabbits are also has antihypertensive effect, and can block the superior cervical ganglion of cat impulse conduction, so with the six hydrocarbon quaternary ammonium ( C6 ) the same. On isolated rabbit intestine can cause tension rises, atropine may block.
[ function ]" Outline": about attending treatment of low back pain. Scrofula.
[ ] cure backache attached side: two two ( the old bat cane three two ), wine two agents decoction. (" Dan" in test efficiency. )
[ note ] the goods in the Jiangsu area for Sabia use, and exported his province.
[ ] * dictionary" excerpt"
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