Equisetum pratense

[ ] C o W Pinyin name be keyword n J n to be
[ alias ] horse beard
[ source ]
Medicine source: Equisetaceae grass ask the whole grass type.
Latin animal mineral name: Equisetum pratense Ehrh.
Harvest and storage: the summer excavation, washed, dried or fresh.
[ ] the original morphology of Equisetum pratense, perennial, high 15-50cm. Rhizomes horizontal, black brown. Spring sporangium stems slightly fleshy, pale brown, with dense green round branched. Leaf sheaths ca.1.5cm, tooth separation sheath, triangle, long point, central Tan, margin white, membranous. Nutritional stems single, sharp wave ridge and spines, branches slender, often level or at right angles to launch.. Spore spike blunt; spores mature stem apex withered branches, to produce green, gradient, and nutritional stems from the same.
[ ] habitat distribution
Ecological environment : in forest, forest edge, shrub and weeds ravine at.
Resource distribution: distribution in the northeast, north, northwest and Hubei.
[ character ] character identification, the whole plant dry shrinkage, branches often fall off. The stems have many whorls of slender branches. Tooth separation sheath, triangle, which is of 1.5cm length, apex acute, mid brown, white membranous edges. Gas, light.
[ ] the chemical composition from - 3 - Double glucoside ( kaempferol-3-diglucoside ), kaempferol - 3 - rutinoside ( kaempferol-3-rutinoside ), kaempferol - 3,7 - Double glucoside ( kaempferol-3-diglucoside-7-glucoside ), quercetin - 3 - rutinose - 7 - glucoside ( quercetin-3-rutinoside-7-glucoside ) ( quercetin ), quercetin, kaempferol ( kaempferol ).
Pharmacological action [ ]
1antihypertensive effect, grass ask type water extract (1:1) in rabbits with different routes of Administration ( gavage, abdominal amine injection, intravenous ) have very significant antihypertensive effect, oral antihypertensive maintain 3-6h, a political decline in blood pressure31.2% ( average), repeated application of rapid tolerance. The water extract of Equisetum pratense to acetylcholine hypotensive effect of sensitizing, M cholinergic receptor block drug products to a plug, the antihypertensive effect abate or disappear. Grass No.1Jing inhibit adrenergic pressor effect; for the occlusion of the common carotid artery blood flow induced pressor response inhibition; cut off the fan out of nerve after antihypertensive effect significantly weakened, so that a central inhibition of Equisetum pratense.
2against myocardial ischemia, Equisetum pratense extract extract (1g crude drug / ml ) intravenous injection of 1.5-3.0g / kg on guinea pig by the thriving and prosperous body posterior lobe hormone induced by standard II leads ECG S-T segment and T wave amplitude increased, slowing of the heart rate, have significant antagonism. The electrocardiogram RR, PQ, OT and ORS interval is administered before significant extension. Equisetum pratense extract 10-15g / kg mice were given intraperitoneal injections, can improve the low voltage and under conditions of hypoxia tolerance, enhanced given induced by isoproterenol hypoxia tolerance, so that the oxygen consumption in mice rate than the control group decreased 32.8%. Myocardial86Rb uptake rate in the low dose group (10g / kg ) and high dose group (15g / kg ) than in the control group were decreased by 8.2%,26.4%; and against isoproterenol induced myocardial and plasma Camkp were increased.
3CNS depression, use of Equisetum pratense extract0.2g / 10g or 0.4g / 10g mice were given intragastrically can strengthen the hypnotic effects of the sodium pentobarbital, the last time required shrinkage rent and sleep time extension of yesterday. Equisetum pratense on 0.2g / 140g abdominal loved people administration to mice, there is weak against, Ning Jingjue effect, can prolong the latency of the same dose of Jing Jue; also can prolong the mice to Nikethamide Jing Jue latency. In the hot plate method proof of Equisetum pratense extract0.2g / 10g intraperitoneal injection has obvious analgesic effect.
4 toxicity, Equisetum pratense extract to mice by intraperitoneal injection of LD50was 38.9 + / -2.66G / kg, after administration of the drug20min, mouse activity weakened, ptosis, reflective retardation, poisoning the righting reflex disappear. Equisetum pratense extract1mg / ml to 0.3ml / min constant rate intravenous, drug after a mean of 40.4+ / -3.6nub, ST, T waves appear markedly or inverted, QRS prolongation or arrhythmia. Minimum toxic dose of 26.4 + / -1.95g / kg; minimum lethal dose of 31.3+ / -1.7g / kg.
[ ] bitter taste; flat
[ function ] Huoxue attending; diuretic; anthelmintic. Atherosclerosis of aorta; painful urination adverse; intestinal parasites.
[ usage] oral administration of Decoction: fresh goods,5-10g,30-60g.
Excerpts from" Chinese Materia Medica" [ ]

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