2012年3月25日星期日

Grass of Fritillaria

[ source ]" selected medicinal plants of Yunnan"
[ ] C o B Pinyin name be keyword I M and
[ alias ] of Bolbostemma paniculatum (" selected medicinal plants of Yunnan" ), adder's-tongue (" Tianjin medical communication" (10) : 16 ~221971.)
[ source ] is a liliaceous plants Lijiang arrowhead mountain bulb. Summer, autumn excavation.
[ ] the original morphology of perennial herbs, about 20 cm high. Bulb ball shape, diameter of about 1 cm, skin brown. Stems single, embedded parts of white, partially excavated with purple. Leaves linear, ca. 15cm, ca. 0.5 cm wide, apex acuminate, base sheathlike, having parallel longitudinal veins. Flowers purple, diameter 1.5 ~2 cm, inflorescence racemose, with 2 to3 flowers. Perianth lobes 6, separation; stamens 6, anthers inside. Capsule oblong, ca. 7 mm wide. Fl. summer.
[ ] habitat distribution was born in grassland or forest hill. The distribution of Yunnan, Tibet and other places.
[ ], the chemical composition of bulb stem, leaves, seeds, containing colchicine colchicine colchicine beta light, angle, N - formyl - N - deacetylase alkaloids such as colchicine.
[ ] the toxicity of Asarum contain large amounts of colchicine, taken orally after in vivo oxidation oxide two colchicine, are highly toxic, the digestive system, urinary system has serious irritation symptoms, to restrain the function of the nervous system, producing ascending paralysis, such as involving the diaphragm caused respiratory dyskinesia. Serious person can produce water and electrolyte balance disorder, caused by low potassium, low chlorine, alkali or acid poisoning, appears of different level of shock symptoms, even may be due to respiratory failure. Colchicine in vivo 24 hours total amount not exceeding 6 mg, the lethal dose is about 20~ 20mg. If the emergency escape, later period can have bone marrow hematopoietic dysfunction, decrease of white blood cells. When the first aid to symptomatic treatment, prevention of complications for the principle, namely, gastric lavage, catharsis, infusion, adjust the electrolyte balance, anti - shock, oxygen and other. The latter to cell growth promoting substance, is expected to restore. Because the symptoms of poisoning and atropine effect is similar, therefore atropine not to.
[ ]" the taste of selected medicinal plants of Yunnan": bitter, temperature, toxic.
[ function ]
Asthma, cough, analgesic, anti. Treatment of bronchitis, asthma, cancer, nasopharyngeal carcinoma.
The clinical application of [ ]
Treatment of breast cancer with bulbus and alkaloids: a mountain arrowhead powder: use bulbus bulb section milling, pack of 0.5grams,1 bag each time,4 times a day, a total of 40to 50 grams for a course of treatment. Two glory81 injection: each containing colchicine 1 mg, each2,5% glucose solution500 ml diluted after intravenous infusion,1 times a day, a total of 40~ 60mg for a course of treatment. Three glory81 - a film by colchicine derivatives: i.e. colcemid made, each containing colchicine amide2.5 mg,2 tablets each time,4 times a day, a total of 400to 500mg, efficacy and glory with 81, and the side effect of reducing. Four glory81 - A injection:10 mg per Zhi Hanqiu daffodils amide. Each of the 1teams, with81injection injection method and glory, a total of 250~ 800mg. Application of the4 kinds of agents in the treatment of61 cases,56cases to see different degree of narrowing, efficiency is 86.1%;5 cases of 17 cases of mass disappeared, reduced to the original volume of more than half of. Which by glory81injection in the treatment of47 cases, effective rate was 93.6%, markedly effective in 42.5%. Route of administration by intravenous infusion effect is good.
Glory of more than 81in15~ 20 mg of medication side effects,80% of the patients the onset of anorexia, abdominal bloating, constipation and other symptoms,70% patients have weakness and joint pain,30% patients with palpitation, finger numbness,5% of the patients body temperature. Stop the medicine 2~ 3days after symptoms disappear gradually (also based on clinical symptoms diagnosis to take medicine to ease symptoms), then to continue medication side effects resulting from the late lighter. Glory - a81injection to 100 mg or more,40% of the patients showed mild loss of appetite, fatigue, palpitations and other symptoms; drug use to more than 300 mg of hair loss can occur. Oral administration of81- piece honor only mild loss of appetite, oral Asarum powder can produce mild nausea, or defecate time compress increase. Application of Asarum and alkaloids, a minority of patients with leukopenia, but discontinued 1weeks after recovery, none of the 1 patients with interrupted due to treatment. On the liver and kidney function and electrocardiogram examination revealed no drug damage, but there were 3 cases of medication after diabetes, its reason to be studied.
[ ] * dictionary" excerpt"


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