Perilla leaf

[ source ]" classics" from Chinese materia medica.
[ ] B I S Pinyin name 's reports the Y keyword
English name [ ] Leaf of Common Perilla
[ alias ] common perilla leaf
[ source ]
Source: Medicinal Labiatae perilla leaves for.
Latin animal mineral name: Perpilla frutescens ( L. ) Britt.
Harvest and storage: summer and autumn harvest, the ventilation dry. Or even the tender stems harvested, cut into small pieces, dried.
[ ] the original morphology of annuals, high 0.5-2m. Stems erect, blunt four prismatic, with four grooves, densely villous. Leaves opposite; to handle long 3-5cm, dorsoventrally flattened, tight end mucronate or cusp, base rounded or broadly cuneate, margin coarsely serrate at above base, two green, or purple, puberulous above. Verticillaster 2 flower, growing group of 1.5-15cm, densely villous, bias towards the side of the terminal and axillary racemes; bracts broadly ovate or suborbicular, outside the red brown glandular, margin membranous; pedicels densely pilose; calyx campanulate, 10 veins, lower pilose, with yellow glands the inner surface of the larynx, sparsely pilose ring, fruit enlargement, calyx mast two lip, upper lip wide, 3 teeth, tooth in the smaller, lower lip slightly longer than 2 teeth, teeth, skin needle; corolla usually white, corolla tube short, limb nearly two 2-lipped, upper lip emarginate, labium 3 crack, in larger lobes; stamens 4, anterior to the slightly longer, free, inserting raw throat, anther locules 2; style apex 2 lobed; disk front finger-shaped enlargement. Nutlets subglobose, with reticulate. Flowering of 8-11 months, fr. 8-12.
[ ] with the chemical composition of Perilla perilla ketone ( perillaldhyde ), (perillake-tone ), incense to ketone (elsholtziaketone), ( limonene ) - limonene, pinene ( pinene ), Nutmeg ether ( myristicin ), dill oil brain ( dillapiol ) [1, 2], stigmasterol ( stigmasterol ) [3 ].
Pharmacological action [ ]
1 the effects on the nervous system of mice fed with common perilla leaf methanol extract 2G / kg, can make the intraperitoneal injection of sodium pentobarbital sleeping time loop has been extended 84%. Volatile oil of main effective components of Perilla aldehyde and stigmasterol [1 ]. Leaf extract from Perilla L, limonene, perilla ketone, elsholtzione, Nutmeg ether and dill oil brain chemistry type compound, each to when to extract 2G / kg for oral administration in mice, has also prolonged pentobarbital sleeping time effects, including dill oil brain and Nutmeg ether type compound leaf extract the strongest effect [2 ].
2 laxative effect of perilla ketone substances ( PK ) leaf extract 1g / kg oral, possibility of significant promotion in mouse small intestine contents advance, 0.25g / kg dose that is to have this role. The category PK substance to isolated from perilla ketone 19mg / kg promotes intestine contents advance rate of up to 138%, in the 3.8-15mg / kg dose dependence test, oral 15mg / kg function peak, oral administration of ED50 11.0mg / kg. PK15mg / kg, 60mg / kg was infused into the duodenum, also can make the small intestine contents in advance by the country. In vitro jejunal longitudinal muscle incubated liquid is added with 10-6g / kg, 10-5g / ml, and 10-4g-ml PK, there is a dose-dependent relaxation effect. While 10-5g / kg PK agent, it can stimulate the circular muscle motility, relaxation in longitudinal muscle [3 ].
3 to escape immune system the effects of perilla leaf juice to mice by intraperitoneal injection, can make the peritoneal exudate neutrophil accumulation. Leaf juice can also make the molding and rise high serum levels of tumor necrosis factor drops. Perilla leaf anti allergic substances in vitro have direct inhibition of macrophage to produce the ability of TNF. Perilla extract can inhibit the production of IgE [4 ].
Antibacterial effect of 4 common perilla leaf be Britt seed oil on inoculation and natural spilled stained bacteria ( Proteus ) ( yeast, fungus, Aspergillus and Penicillium ) can inhibit aldehyde, pinene, limonene extraction liquid oral infection with Pseudomonas aeruginosa can prolong the survival rate of mice [6 ].
5 other roles from Perilla in compound with xanthine oxidase inhibitory effect, but the treatment of gout [7 ]. Su Ziquan white grass hot water extract of 100 u g / ml Cynanchum phosphodiesterase inhibitory activity for an average of 36.2%, wherein the chloroform soluble fraction ( CHCI3 ) inhibitory activity of 62.6%, insoluble fractions of CHCI3 almost no inhibitory activity [8 ].
6 toxic and side reaction of perilla ketone in mice by oral administration of LD50 for 78.9mg / kg, intraperitoneal injection of LD50 13.6kmg-kg. Another report of perilla ketone to intraperitoneal injection of mouse male mice, LD50 6mg-kg, 2.5mg / kg female mice. Cows intravenous about 30mg perilla ketone 10h can cause respiratory symptoms, 3D after death. 19mg / kg dose continuous intravenous injection for sheep, will also have a respiratory system adverse reaction, but the 5D recovery [9 ]. Perilla ketone to sheep fed with the 40mg / kg, live. Mouse peritoneal injection of 10mg / kg, 24h death, and visible extensive pulmonary edema and peritoneal exudate [10 ]. 15mg / kg, 20km / kg, 25mg / kg perilla ketone to in vivo sheep blood perfusion, can increase the pulmonary microvascular permeability function, make the extravascular lung secretions increase, severe pulmonary edema [11 ].
[ ] taste acrid in taste and warm;
[ ] the lung meridian; spleen meridian
[ ] functions of dispelling wind and dispersing lung qi; digestion, solving toxin of fish and crab. The main cold; cough and asthma; abdominal distension Wan stuffy; weak; vomiting; cold dysentery; fish crab poisoning; man Yin is swollen; limb emphysema poison; snake bites
[ usage]: orally taken decoction, 5-10g; or at the end of the inquiry. External: moderate, and vinegar mash deposition.
[ ] the discussion
1:" don't record" theme, to smell.
The 2" Chinese Materia Medica": a trace and apply bug.
3" Hua Zi": a gas regulating herbal heart lung, skin color, long, benefit, eliminating old food, only gas to cough, body odor, apply the snake.
4" South Yunnan Materia Medica": treatment of typhoid fever, no sweat, headache, cold phlegm in all nodes, cholera cramp, cough spit, pediatric wind disease. Pain, zhichuan.
5" herbs of preparing to": under the gas, in addition to rheumatism.
6" Fujian folk medicine": elimination of cold, cold wind and stopping dysentery, fever, insect detoxification.
Excerpts from" Chinese Materia Medica" [ ]
http://chinese-herbal-medicines-directory.blogspot.com/