Marijuana Ye Peilan

Pinyin name ] [ Dà Má Yè Pè I Lá n
[ source ]
Medicine medium source: as the Compositae marijuana Ye Zelan entire grass.
Latin botanical name: Eupatorium cannabinum L. animal fossil
Harvest and storage: summer flowers not open when the harvest, except as sediment, dried in the sun or shade.
[ ] the original morphology of marijuana Ye Zelan perennial is herbaceous, tall 50-150cm. Roots thick, with numerous rootlets, students. Stems erect, all or part of purple red, unbranched or only in the stem top having corymbose inflorescence branching, all the stems and branches, pubescent, inflorescence branches and pedicels densely hairy, when flowering in the lower part of hair removal. Leaves opposite; a short handle, stipe ca.0.5cm; in the lower stem leaves in three cleft, lobes, oblong or long lanceolate, long 6-11cm, wide 2-3cm, apex acuminate or long acuminate, base cuneate or broadly cuneate, lateral lobes small, in the same shape and lobes; upper stem leaf tailed, three lobed or unlobed, lower stem leaves of flowering stem and leaf litter; all sides of coarse texture, slightly thick, is sparsely white pubescent and glandular dots below, below and along veins hair dense, margin serrate. Heads in the majority, shoot tip and branch end row will set the answer umbrella compound corymb; involucre campanulate, ca.6mm, containing 3-7florets; involucre campanulate, ca.6mm, containing 3-7florets; involucral bracts9-10,2-3layer, outer layer of short, ovate-lanceolate, ca.2mm it is short, soft hairs, in Inner bracts grew, lanceolate, long 5-9mm, margin membranous, apex acute, and dyed purple; flowers purplish red, pink or white light, corolla ca.5mm, tegument sparse yellow glandular dots. Achenes dark brown, terete, ca.3mm,5 prism, scattered yellow glandular dots; crested white, ca.5mm.
[ ] habitat distribution
Ecological environment : in grass slope or village near bamboo forest.
Resource distribution: located in Jiangsu, Zhejiang.
[ character ]
Character identification: whole plant pubescent, thick stem, base ministry lignification. Leaves opposite, with a short handle, much shrinkage, green or yellowish green, in the lower part of stems and leaves in three cleft, lobes, complete flat after a long oval or long lanceolate, long 6-11cm, wide 2-3cm, apex acuminate or long acuminate, base cuneate or broadly cuneate, upper stem leaves gradually small. Micro gas smell, taste bitter.
Microscopic identification of leaf surface view: epidermal anticlinal wall winding, stomatal infinitive, its surrounding epidermal cells are radially horny texture, leaves and veins than there were two types of glandular hairs, a slightly clavate, by 4-6cell composition, length of 90-130-160μ m,12-16μ m in diameter, thin wall; another is a long conical, made up of 2-7cell composition, length of 76-300μ m,18-48μ m in diameter, wall thickness. Glandular head is composed of 4 cell composition, diameter 40-50 μM. On the surface pores and less hairy.
Ye Heng: special-shaped blade section. On the lower epidermis, outside layer texture was slightly were dentate, non glandular hairs and glandular hairs in many. Palisade cell2, cylindrical, second rows of cells arranged in loose. A short, grid cells but the main vein. The main vein vascular6omitted a semicircle, vascular bundles between secretory cavity dispersion in. Main veins under the skin of medial2-3 layers of collenchyma cells.
The transverse section of the stem: slightly flat hexagonal. Epidermal cells small, square or rectangular, the epidermis has many non glandular hairs. Under the skin of3-10 layers of collenchyma cells, cortical parenchyma cells in8-10layer. More than 20ranging from the size of the vascular bundle arranged in a ring, at the corner of the bundle is slightly big. Phloem is narrow, vascular bundles inside and outside are fiber bundles, a half-moon, small vascular bundle only phloem outside of a fiber bundle. Cambium cell2-3 column into a ring; xylem by catheter, catheter consisting of fibers, single row. Central to the spinal cord, and secretory canals are scattered in the.
[ ] the chemical composition
1root and aboveground part contains alkaloid, has isolated: supine heliotrope alkali ( supinne ), echinatine ( echinatine ), ( trachelanthamine) fiddleneck amine,β- isobutyryl supine heliotrope alkali (β -bu-tyrylsupinine ),β- isovaleryl supine heliotrope alkali (β -valeryl-supinine ),β- acetyl echinatine (β -acetylechinatine ),β- isovaleryl thorn de alkali (β -isovalerylechinatine ),β- Angelica acyl / crotonic acid supine heliotrope alkaline (β -angeloyl/tigloyl supinine ),β- Angelica acyl / crotonic acid thorn de alkali (β -angeloyl/tigloylechinatine)β- Angelica acyl acyl amine ( neck / Croton flowerβ -angeloyl/tigloyltrachelanthamine ); also containing sesquiterpene lactone ingredients: weed lactone ( eupatolide ), ( eupatoriopicrin ) from bitter elements,3- acetyl -20- DNA from bitter elements (3-acetoxy-20-deoxyeupatoriopicrin ),3- acetyl - two DNA from bitter elements (3-acetoxy-dideoxyeupatoriopicrin ),3 β - hydroxy adenophorum bitter elements (3 β -hydroxyeupatoriopicrin cannabis ), Ye Peilan ( eucannabino-lide ), bitter lactone from -19-O- linolenic acid ester ( eupatoriopicrin-19-O-1inolenate ),8 β- acetyl hydrogen based -2 α- hydroxy costunolide (8 β -acetoxy-2,α -hydroxycos-tunolide,2- b ) Acyl -8 β- (4,5- two hydroxy Croton acyloxy ) before Ye Zelan circle lactone [2-acetyl-8β- (4,5-dihydroxytigloyloxy ) preeupatundin],6- hydroxyl acrylic furosemide benzophenone (6-hydroxytremetone ), Sakhalin Island North Angelica lactone ( sachalinin ),3 β- Angelica acyloxy6- hydroxyl acrylic furosemide benzophenone (3 β -angeloyloxy-6-hydrox-ytremetone ),3 β- isobutylene acyloxy -6- hydroxyl acrylic furosemide benzophenone (3 β -methacry-loxy-6-hydroxytremetone ),3 β- isobutyl acyloxy -6- hydroxyl acrylic furosemide benzophenone (3 β -isobutyryloxy-6-hydroxytremetone ), marijuana, Ye Peilan Crowe alkyl lactone ( cannaclerodanolide ), alantolactone ( alantolactone ), isoalantolactone ( isolantolanctone ), Shanlan lactone ( hiyodorilactone ) E, to acetyl oxygen Jishanlan lactone (desacetoxy hiyodorilactone ) B, Taiwan ( eupaformonin ) and other weed lactone.
2 contain flavonoids: hispidulin ( hispidulin ), cuneus adenophorum hormone (eupafolin), Kiwoon E ( astragalin ), Hyperoside ( Hyperoside ), kaempferol -3- rutinoside ( kaempferol3-rutinoside ), Isoquercitrin ( Isoquercitrin ), rutin ( rutin ), toadflax hormone ( pectolinari-genin ),4 ′, three′-5,7- -3,6- two methoxy flavone ( jaceosidin ),5,7- two hydroxy4 ', -3,6- tertiary hydrogen radicals flavonoids ( Santin ), Centaurea Flavin (centaureidin) etc..
3: stigmasterol sterols ( stigmasterol ),β- sitosterol (β -sitosterol ), campesterol ( campesterol ), dandelion sterols (taraxasterol); other ingredients: bluegrass hormone ( euparin ),10- acetyl nerol acetate (10-acetoxynerylacetate ), lutein ( Lutein ),4- hydroxyl violet ketone (4-hydroxyionone ), ( E ) -1- hexenoic acid [ (E) -hex-1-enoic acid], big Mang cattle by (germacrene ) D, neryl acetate ( neryl acetate ), valeric acid nerol acetate ( nerylisovaler-ate ), neryl isobutyrate ( neryl isobutyrate ), Dama two enol acetate (dammaradienyl acetate ).
The 4ground part contain approximately 0.3% volatile oil, there are: aldehyde (n-octanal), acetic acid ethyl ester ( hexylacetate ), pelargonic aldehyde ( n-nonanal ), acetic acid heptyl alcohol ester ( heptylacetate ), capric aldehyde (decanal ), acetic acid ( octyl acetate ) octanoic acid ester, methyl salicylate ( methyl salicylate ), linalool esters of acetic acid ( linalyl acetate ), bornyl acetate ( bornyl acetate ), acetic acid alcohol ester ( lavandulyl acetate ) of lavender, crotonic acid ester (3-Hexenyl tiglate -3- hexenol ), neryl acetate, acetic acid benzyl ester ( ben-zyl acetate ), geraniol acetate ester ( geranylacetate ), Citronellyl acetate ( Citronellyl acetate propionic acid ), borneol ester ( Bornyl propionate ), thymohydroquinone two ether ( thymohydroquinone dimethylether ),α - terpineol acetate propionate (α -terpenylpropionate ), nerol propionate ( nerylpropioriate ), butyric acid thyme phenol ester ( thymylbutyrate ), botnyl isovalerate ( bornylisovalerate ),α - terpineol acetate butyrate (α-terpenyl butyrate ), CIS -3- hexenol benzoate ( cis-3-hexenyl benzoate ), isoamyl acid thyme phenol ester ( thymylisovalerate ), valeric acid nerol acetate, isovaleric acid geraniol acetate ( geranylisovalerate ), crotonic acid thyme phenol ester ( thymyltglate ), benzene Benzoic acid benzyl ester ( benzylbenzoate ) and other ingredients. Also, the grass in the volatile oil of -5- containing 2- isopropyl methyl ethyl ether (2-isopropyl-5-methylanisole ) and other 38 kinds of composition.
[ ] the pharmacological effect
1: Ye Perrin Shui hepatoprotective effects of cannabis extract in mice induced by carbon tetrachloride given before, can reduce blood alanine aminotransferase activity, but after the poisoning of invalid. The bitter elements in Eupatorium extract contains concentrations without liver cytotoxicity.
2: the cytotoxicity of human small cell lung cancer cell line test, marijuana Ye Peilan in Eupatorium bitter components have higher cytotoxicity, ID50 is about1 μ g/m1-2 μg/ml; weed lactone in these concentrations had no effect.
3other roles: from marijuana Ye Peilan obtained in the polysaccharides in human granulocyte test and animal carbon clearance test, showed immune stimulating activity.
[ ] taste spicy; flat
[ indications ] Qingshu; monarchs dirty wet. The main summer summer fever closed injury; pain; wet evil connotation, digestive tract infection hunger; bitter taste greasy fur
[ usage]: orally taken decoction,4-9g.
Excerpts from" Chinese Materia Medica" [ ]

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